Guillainbarre syndrome gbs is an acute polyneuropathy with a variable degree of weakness. Guillainbarre syndrome loma linda university childrens. Objective clinical characteristics of pediatric guillainbarre syndrome gbs have been extensively studied whereas scarcely been compared. The acute immunemediated polyneuropathies are classified under the eponym guillainbarre syndrome gbs, after the authors of early. Early guillainbarre syndrome in coronavirus disease 2019.
Prospective health care data routinely collected for administrative purposes may represent a. Under the umbrella term of guillainbarre syndrome are several recognisable variants with distinct clinical and pathological features. The full text of this article is available in pdf format. Guillain barre syndrome gbs is a shortterm but often lifethreatening disorder that affects the nerves in the body.
It is characterized by abnormal muscle coordination with poor balance and clumsy walking, weakness or paralysis of the eye muscles, and absence of the tendon reflexes. Guillainbarre syndrome in children childrens hospital of philadelphia. Pediatric guillainbarre syndrome in a 30year nationwide. Guillainbarre syndrome gbs is a temporary neurological disorder in which a childs immune system attacks part of the peripheral nervous system. Guillainbarre syndrome gbs is an acute polyradiculoneuropathy characterized by progressive motor weakness of limbs and areflexia. Guillain barre syndrome gbs is an acquired disorder of the peripheral nerves, described best as a polyradiculoneuropathy. Guillain barre syndrome gbs is an acute, immunemediated polyradiculoneuropathy with a wide range of clinical manifestation. It is the leading cause of acute flaccid paralysis in developed countries, in which polio has been eradicated 2. Neurologic problems persist in up to 20 percent of patients with the disease, and onehalf of these patients are severely disabled. Guillainbarre syndrome in children childrens hospital. Diagnosis, treatment and prognosis of guillainbarre syndrome gbs. Guillainbarre syndrome fact sheet national institute of. The guillainbarre syndrome gbs is an acute immunemediated polyneuropathy considered as the most common causes of acute flaccid paralysis in healthy.
Prognosis of guillainbarre syndrome in children ncbi. Gbs can cause muscle weakness, pain, and shortterm temporary paralysis of the muscles in the face chest, and leg and those used to swallow. Understand how to rule out other potentially dangerous and treatable causes of weakness and paralysis in children. Clinical features and outcome of guillainbarre syndrome in children. Guillainbarre syndrome is a rare disorder that causes your immune system to attack your peripheral nervous system pns. Millerfisher syndrome is a rare, acquired nerve disease that is a variant of guillainbarre syndrome. Guillainbarre syndrome gbs is an acuteonset, monophasic, immunemedi ated polyneuropathy. Understand the management of the child with guillain barre syndrome. Guillain barre syndrome gbs is classically defined as an. Guillainbarre syndrome is the most common and most severe acute paralytic neuropathy, with about 100 000 people developing the disorder every year worldwide. Guillainbarre syndrome american academy of pediatrics.
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